代謝物受託製造の株式会社TOPUバイオ研究所

医薬品・食品由来成分の代謝物の受託製造、代謝スクリーニング試験、代謝物標準品の提供を行っています。

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TOPU BIO Research

Biosynthesis of human drug metabolites

We provide P450s and phase II (e.g. UGTs, SULTs and COMT) metabolites of drugs, environmental compounds and several food factors such as polyphenols.
We developed biosynthetic platform using mammalian DME expression systems in yeast.

Would you have any trouble in preparing desire metabolites?
Our technology would help you study on drug metabolism.

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We have developed drug metabolite preparation system using genetically modified yeast cells. Metabolites can be used for analytical standards, structural confirmation and test compounds for evaluation.
We have abundant line-up of recombinant drug metabolizing enzymes in yeast cells such as  CYPs, UGTs, SULTs and so on. We also have animal tissue fractions.


 
 
Case studies for metabolite preparation


We want to hear about your questions or concerns.
Please feel free to contact us with the form.

Company profile

Company Name
TOPU BIO Research Co., Ltd.
Office
Imizu Research Center
5180 Kurokawa, Imizu-shi, Toyama 939-0398, Japan
Established
April 1st, 2011
Capital
8,000,000(JPY)
President
Miyu Nishikawa DVM Ph.D
Directors
Yasuhisa Asano Ph.D
Toshiyuki Sakaki Ph.D
Hiroshi Sakai
Yohei Hayashi
Adviser
Toshio Chow Ph.D

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